Linkage exclusion mapping: rare diseases get SAMPLE'd
نویسندگان
چکیده
منابع مشابه
Exclusion mapping.
The basis for using information against linkage to some loci to support linkage to other loci is discussed and data on cystic fibrosis available up to late July 1985 used as an example.
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1. Abstract 2. Introduction 3. Models and methods 3.1. Haplotype block characterization 3.2. Measure of haplotype block LD 3.3. Test statistic and power calculation 3.4. Population genetic model of haplotype block 4. Results 4.1. Haplotype block LD measure 4.2. Power of the haplotype block LD mapping 4.3. Mapping 5. Discussion 6. Appendix 6.1. Appendix A 6.2. Appendix B 6.3. Appendix C 7. Refer...
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ژورنال
عنوان ژورنال: Human Mutation
سال: 2009
ISSN: 1059-7794,1098-1004
DOI: 10.1002/humu.21161